Calciphylaxis

Overview

Calciphylaxis (kal-sih-fuh-LACK-sis) is a serious, uncommon disease in which calcium accumulates in small blood vessels of the fat and skin tissues. People who have this condition usually have kidney failure and are on dialysis or recently had a kidney transplant. Calciphylaxis causes painful skin ulcers and may cause serious infections that can lead to death.

Why choose Mayo Clinic for calciphylaxis

• Expertise and experience. Even though calciphylaxis is uncommon, Mayo Clinic doctors have the expertise and experience to diagnose and treat this disease.
• Multispecialty team. Calciphylaxis is a complicated disease that can affect different organs. Mayo's specialists in nephrology, dermatology, plastic surgery, endocrinology, infectious disease and other areas as needed work together to treat people with calciphylaxis.
• Cutting-edge treatment. Mayo Clinic doctors use a three-pronged approach to treat calciphylaxis that includes decreasing calcium accumulation, restoring blood flow and intensive wound treatment. Mayo Clinic dermatology pioneered the use of low-dose tissue plasminogen activator (TPA) to dissolve tiny blood clots in calciphylaxis.

Mayo Clinic in Rochester, Minn., and Mayo Clinic in Scottsdale, Ariz., are ranked among the Best Hospitals for kidney disorders by U.S. News & World Report. Mayo Clinic in Jacksonville, Fla., is ranked high performing for kidney disorders by U.S. News & World Report.

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At Mayo Clinic, we assemble a team of specialists who take the time to listen and thoroughly understand your health issues and concerns. We tailor the care you receive to your personal health care needs. You can trust our specialists to collaborate and offer you the best possible outcomes, safety and service.

Mayo Clinic is a not-for-profit medical institution that reinvests all earnings into improving medical practice, research and education. We're constantly involved in innovation and medical research, finding solutions to improve your care and quality of life. Your doctor or someone on your medical team is likely involved in research related to your condition.

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