Doctors utilize many conditioning options to kill cancer cells and suppress your immune system prior to your bone marrow transplant. Reduced-intensity conditioning may be an option if you're receiving stem cells from a donor in a bone marrow transplant (allogeneic bone marrow transplant).
In reduced-intensity conditioning, you're given lower doses of chemotherapy or radiation prior to your transplant. This kills some cancer cells and somewhat suppresses your immune system. Then, the donor's cells are infused into your body. Your donor's cells replace cells in your bone marrow over time and may then fight your cancer cells.
This less intense conditioning option may be appropriate for people who aren't healthy enough for conditioning or people who are older. Your doctor will discuss with you which type of conditioning may be most appropriate for you, considering several factors, including your age, medical condition and health.