1. Minnesota


  1. Cancer Center
  2. Orthopedic Surgery


  1. Postdoctoral Fellowship - Molecular Biology Vanderbilt University
  2. Post Doctoral Fellowship - Tumor biology St. Jude's Children's Research Hospital
  3. PhD - Biomedical Sciences-Immunology Ph.D. Program, Mayo Graduate School, Mayo Clinic College of Medicine
  4. PhD Immunology, Programs, Mayo Graduate School, Mayo Clinic College of Medicine
  5. BA - Biology and Chemistry University of Minnesota, Morris

Primary Appointment

  1. Orthopedic Surgery

Academic rank

  1. Professor of Orthopedics
  2. Professor of Biochemistry and Molecular Biology


  • Mechanisms whereby the transcription factors, Runx2 and Lef1, regulate gene expression in osteoblasts
  • Determine how multiple repression domains in Runx2 mediate interactions with other proteins to contribute to transcription repression
  • Define how the interactions of three histone deacetylases and a transcription factor (Lef1) with Runx2 are regulated during osteoblast differentiation and cancer-induced bone disease
  • Define how Runx2 complexes contribute to bone formation and metastatic cancer


See my publications


See a description of research activities.