Location

  1. Minnesota

Departments

  1. Orthopedic Surgery

Education

  1. Postdoctoral Fellowship - Molecular Biology Vanderbilt University
  2. PhD Immunology Track, Mayo Graduate School, Mayo Clinic College of Medicine
  3. PhD - Biomedical Sciences-Immunology Ph.D. Program, Mayo Graduate School, Mayo Clinic College of Medicine
  4. Post Doctoral Fellowship - Tumor biology St. Jude's Children's Research Hospital
  5. BA - Biology and Chemistry University of Minnesota, Morris

Academic rank

  1. Professor of Biochemistry/Molecular Biology
  2. Professor of Orthopedics

Interests

  • Mechanisms whereby the transcription factors, Runx2 and Lef1, regulate gene expression in osteoblasts
  • Determine how multiple repression domains in Runx2 mediate interactions with other proteins to contribute to transcription repression
  • Define how the interactions of three histone deacetylases and a transcription factor (Lef1) with Runx2 are regulated during osteoblast differentiation and cancer-induced bone disease
  • Define how Runx2 complexes contribute to bone formation and metastatic cancer

Publications

See my publications

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