Amyloidosis

Symptoms

Indications of amyloidosis can vary considerably and depend largely on the organs affected. The extreme range of symptoms and other physical manifestations can make amyloidosis difficult to diagnose; in some cases, no symptoms develop. Some common signs and symptoms include:

• Swelling of the ankles and legs
• Weight loss
• Shortness of breath
• Diarrhea
• Severe fatigue
• An enlarged tongue (macroglossia)
• Skin changes
• Irregular heartbeat
• Weakness
• Difficulty swallowing
• Numbness or tingling in the hands or feet