Mayo Clinic doctors trained in treating children who have brain and nervous system conditions (pediatric neurologists), doctors trained in brain and nervous system conditions (neurologists), and others work together to determine the most appropriate treatment for people who have adrenoleukodystrophy (ALD).
Adrenoleukodystrophy has no cure. However, stem cell transplantation may stop the progression of ALD if conducted when neurological symptoms first appear. Doctors also will focus on relieving your symptoms and slowing the progression of the disease.
Your treatment options may include:
- Stem cell transplant. Stem cell transplant may be an option to help slow or halt the progression of adrenoleukodystrophy in children if the disease is diagnosed and treated early. Stem cells may be taken from bone marrow through bone marrow transplant.
- Adrenal insufficiency treatment. Many people who have ALD develop adrenal insufficiency and need to have regular adrenal gland testing. Adrenal insufficiency can be treated effectively with man-made (synthetic) steroids (corticosteroid replacement therapy).
- Medications. Your doctor may prescribe medications to help relieve symptoms, including stiffness and seizures.
- Physical therapy. Physical therapy may help relieve your muscle spasms and reduce muscle rigidity. Your doctors will provide recommendations regarding wheelchairs and other mobility devices if needed.
- Genetic counseling. Your treatment may include genetic counseling for you and your family. Mayo Clinic doctors trained in hereditary conditions (neurometabolic specialists) explain your diagnosis and the role of genes in your condition. Doctors strongly recommend that you and your family receive genetic testing and counseling.